RNA polymerase 2 subunit RPB9 (RNA polymerase II p14.5 kD subunit, RPB14.5, RNA polymerase 2 subunit I, POLR2I, RPB9)

Function: - component of RNA polymerase 2 - POLR2I is part of the upper jaw surrounding the central large cleft & thought to grab the incoming DNA template - phosphorylated upon DNA damage, probably by ATM or ATR Structure: - belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family - contains 1 TFIIS-type Zn⁺² finger Compartment: nucleus (putative)

General

nuclear protein phosphoprotein rna polymerase subunit

Properties

SIZE: entity length = 125 aa MW = 15 kD COMPARTMENT: cell nucleus MOTIF: Zn finger C4-type SITE: 17-42 EFFECTOR-BOUND: Zn+2 MOTIF: Zn+2-binding site SITE: 17-17 Zn+2-binding site SITE: 20-20 Zn+2-binding site SITE: 39-39 Zn+2-binding site SITE: 42-42 Ser phosphorylation site {S73} Zinc finger NAME: Zinc finger SITE: 82-124 EFFECTOR-BOUND: Zn+2 MOTIF: Zn+2-binding site SITE: 86-86 Zn+2-binding site SITE: 89-89 Zn+2-binding site SITE: 114-114 Zn+2-binding site SITE: 119-119

Database Correlations

OMIM 180662 UniProt P36954 Pfam PF02150 Kegg hsa:5438

References

UniProt :accession P36954