RNA polymerase II elongation factor ELL2 (ELL2)

Function: - transcription elongation factor - can increase the catalytic rate of RNA polymerase 2 transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA - interacts with EAF1 & EAF2 Structure: belongs to the ELL/occludin family Compartment: nucleus

General

human longevity protein nuclear protein phosphoprotein

Properties

SIZE: entity length = 640 aa MW = 72 kD COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S503} Ser phosphorylation site {S580} Ser phosphorylation site {S604}

Database Correlations

OMIM 601874 UniProt O00472 PFAM correlations Entrez Gene 22936 Kegg hsa:22936

References

UniProt :accession O00472