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risk factors for COPD

Etiology: risk factors - genetic factors - exposure to particles a) tobacco smoke b) occupational dusts (organic & inorganic) 1] coal 2] silica 3] synthetic mineral fibers 4] cement 5] vanadium 6] cadmium 7] cotton, hemp, jute (textiles) 8] grain dust 9] wood (paper mills) c) indoor air pollution - heating & cooking with biomass fuel in poorly ventilated buildings a) welding fumes b) fire, smoke - outdoor air pollution a) smog b) fire, smoke - lung growth & development - childhood risk factors - asthma, allergic rhinitis, bronchitis, pneumonia [2] - smoking, second hand smoke, maternal smoking [2] - oxidative stress - sex - age - socioeconomic status - nutrition - comorbidities

General

health risk factor(s)

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 15, 18. American College of Physicians, Philadelphia 2009, 2018.
  2. Bui DS, Burgess JA, Lowe AJ et al Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome. Am J Respir Crit Care Med. 2017 Jul 1;196(1):39-46. PMID: 28146643 - Bui DS, Lodge CJ, Burgess JA, et al Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life. Lancet Respiratory Medicine. April 5, 2018 PMID: 29628376 http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30100-0/fulltext - Belgrave DCM, Granell R, Turner SW, et al Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies. Lancet Respiratory Medicine. April 5, 2018 PMID: 29628377 http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30100-0/fulltext - von Mutius E Childhood origins of COPD. Lancet Respiratory Medicine. April 5, 2018 PMID: 29628375 http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30141-3/fulltext
  3. Bui DS, Burgess JA, Lowe AJ et al Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome. Am J Respir Crit Care Med. 2017 Jul 1;196(1):39-46. PMID: 28146643 Free Article