Search
ribose-5-phosphate isomerase; phosphoriboisomerase (RPIA RPI)
Function:
- carbohydrate degradation; pentose phosphate pathway;
- D- ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1
D-ribose 5-phosphate = D-ribulose 5-phosphate
Structure:
- belongs to the ribose 5-phosphate isomerase family
Pathology:
- defects in RPIA are the cause of ribose-5-phosphate isomerase deficiency
Laboratory:
- ribose-5-phosphate isomerase in fibroblasts
- ribose-5-phosphate isomerase in lymphoblasts
Related
ribose-5-phosphate isomerase deficiency
General
isomerase
Properties
SIZE: entity length = 311 aa
MW = 33 kD
MOTIF: active site
Database Correlations
OMIM correlations
MORBIDMAP 180430
UniProt P49247
Pfam PF06026
Entrez Gene 22934
Kegg hsa:22934
ENZYME 5.3.1.6
References
- UniProt :accession P49247
- GeneReviews
http://www.ncbi.nlm.nih.gov/sites/genetests/lab/gene/RPIA