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renal fibrosis
Pathology:
- likened to a failed wound-healing process after chronic, sustained renal injury
- mesangial & fibroblast activation
- tubular epithelial-mesenchymal transition
- glomerulosclerosis & tubulointerstitial fibrosis
- end-stage renal disease
Management:
- hemodialysis
- kidney transplantation
General
fibrosis
kidney disease; renal disease
References
- Schnaper HW, Kopp JB.
Renal fibrosis
Front Biosci. 2003 Jan 1;8:e68-86.
PMID: 12456333
- Liu Y
Renal fibrosis: New insights into the pathogenesis and
therapeutics
Kidney International (2006) 69, 213-217
http://www.nature.com/ki/journal/v69/n2/full/5000054a.html
- Shihab FS
Do We Have a Pill for Renal Fibrosis?
CJASN September 2007 vol. 2 no. 5 876-878
PMID: 17702718
http://cjasn.asnjournals.org/content/2/5/876.full