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renal disease in pregnancy
Complications:
increased risk for
- pre-eclampsia
- acute renal failure
- progression of chronic renal failure to end-stage renal disease
- preterm delivery
- gestational hypertension
- intrauterine growth retardation
- fetal loss, stillbirth [1]
- kidney stones in 3rd trimester & 1st 3 months postpartum [2]
- most stones are calcium phosphate (hydroxyapatite)
Management:
- renal transplant patients should wait at least 2 years after transplantation with a stable allograft & stable immunosuppression before attempting conception [1]
- immunsuppressive agents mycophenolate & sirolimus are teratogenic & must be discontinued prior to attempting conception
Specific
acute renal failure in pregnancy
chronic renal failure in pregnancy
General
pregnancy disorder; obstetric disorder; pregnancy complication
kidney disease; renal disease
References
- Medical Knowledge Self Assessment Program (MKSAP) 18,
American College of Physicians, Philadelphia 2018
- Thongprayoon C, Vaughan LE, Chewcharat A et al.
Risk of symptomatic kidney stones during and after pregnancy.
Am J Kidney Dis 2021 Sep; 78:409.
PMID: 33867205 PMCID: PMC8384636 (available on 2022-09-01)
https://www.ajkd.org/article/S0272-6386(21)00402-9/fulltext