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Reinke space

Structure: - loose connective tissue subjacent to the basement membrane of squamous-lined true vocal fold - it is devoid of glandular tissue & lymphatic channels Pathology: - it is prone to react to trauma, either due to smoke, excessive phonation, or other trauma - due to lack of lymphatic channels, edema with increased vascularization, known as Reinke edema may occur may manifest clinically as a polypoid projection into the airway.

General

connective tissue

References

  1. Naunheim NR, Huston MN, Sadow PM et al Polypoid Corditis. Reinke Edema of the Larynx Mayo Clinic Proceedings 2023. 98(1):200-201. Jan 3 https://www.mayoclinicproceedings.org/article/S0025-6196(22)00559-6/fulltext

Component-of

larynx