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redox-modulated transcription factor
One of several transcription factors that is directly influenced by reactive oxygen species & proinflammatory cytokines.
Specific
activating protein 1 (AP1)
LX nuclear receptor (LXR, oxysterol receptor)
nuclear factor kappa-B (NF-kappa B)
peroxisome proliferator-activated receptor (PPAR)
transcription factor Sp1 (SP1, TSFP1)
General
transcription factor (TF)
Properties
COMPARTMENT: cell nucleus
References
- Lavrovsky Y, Chatterjee B, Clark RA, Roy AK.
Role of redox-regulated transcription factors in inflammation,
aging and age-related diseases.
Exp Gerontol. 2000 Aug;35(5):521-32. Review.
PMID: 10978675