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recombinant tissue plasminogen activator (TPA, t-PA, rt-PA,)
see alteplase, alteplase
Notes:
- alteplase is administered by bolus followed by infusion
- reteplase & tenecteplase are administered by bolus
- tenecteplase has the highest fibrin specificity, retelase the lowest
Related
thrombolytic therapy
Specific
alteplase (Activase)
reteplase (Retevase)
tenecteplase (TNKase)
General
tissue-type plasminogen activator; t-PA; t-plasminogen activator; tPA (PLAT)
fibrinolytic agent (thrombolytic agent)
enzymatic agent
recombinant protein; chimer
References
- Medical Knowledge Self Assessment Program (MKSAP) 16, 18
American College of Physicians, Philadelphia 2012, 2018