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reactive perforating collagenosis

Etiology: - inflammatory or malignant systemic diseases may coexist with acquired reactive perforating collagenosis Pathology: - focal hyperkeratosis in direct contact with transepidermal perforating dermal collagen Clinical manifestations: - umbilicated hyperkeratotic papules or nodules Management: - topical treatments - ultraviolet B phototherapy - oral allopurinol

General

skin disease (dermatologic disorder, dermatopathy, dermatosis)

References

  1. Karpouzis A et al Acquired reactive perforating collagenosis: current status. J Dermatol. 2010 Jul;37(7):585-92. Review. PMID: 20629824
  2. Faver IR et al Acquired reactive perforating collagenosis. Report of six cases and review of the literature. J Am Acad Dermatol. 1994 Apr;30(4):575-80. PMID: 8157784