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Ras-GEF domain-containing family member 1B (GPI gamma-4, RASGEF1B, GPIG4)
Function:
- guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro) (putative)
Structure:
- contains 1 N-terminal Ras-GEF domain
- contains 1 Ras-GEF domain
Alternative splicing: named isoforms=3
Expression:
- up-regulated in monocytes stimulated with T.cruzi GPI-anchored mucins or bacterial lipopolysaccharide
General
guanine nucleotide exchange factor (GDP/GTP dissociation stimulator, guanine nucleotide-releasing factor/protein, GNEF, GNDS, GDS)
Properties
SIZE: entity length = 473 aa
MW = 55 kD
MOTIF: guanine nucleotide exchange domain
NAME: guanine nucleotide exchange domain
SITE: 34-164
guanine nucleotide exchange domain
NAME: guanine nucleotide exchange domain
SITE: 204-452
Database Correlations
UniProt Q0VAM2
PFAM correlations
References
UniProt :accession Q0VAM2