rasberry ketone; 4-(4-hydroxyphenyl)-2-butanone

Uses: - weight reduction - food flavoring - perfume in cosmetics Dosage: - 100 mg at breakfast Adverse effects: - androgen antagonist in vitro Mechanism of action: - structurally similar to capsaicin from hot pepppers & synephrine from citrus - increases lipolysis in mice fed high-fat diet - may increase expression of adiponectin - may inhibit fructose-associated fat accumulation - may inhibit fat absorption via reduction of pancreatic lipase activity Notes: - rasberry ketone gives rasberries their odor

References

Prescriber's Letter 19(5): 2012 COMMENTARY: Raspberry Ketone for Weight Loss CHART: Drugs for Weight Loss Detail-Document#: 280503 (subscription needed) http://www.prescribersletter.com