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rasburicase (Elitek)
Indications:
- hyperuricemia
- prophylaxis in tumor lysis syndrome*
- patients with uric acid nephropathy due to tumor lysis syndrome despite prior allopurinol therapy [2]
* single course of therapy only
Dosage:
- 0.2 mg/kg as a 30 minute intravenous infusion daily for up to 5 days
Notes:
- more expensive than allopurinol [2]
General
urate oxidase
recombinant protein; chimer
hypouricemic agent
References
- RxList
http://www.rxlist.com/elitek-drug.htm
- Medical Knowledge Self Assessment Program (MKSAP) 16, 17.
American College of Physicians, Philadelphia 2012, 2015