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Ran-binding protein 2-like 3; RANBP2-like & GRIP domain-containing protein 8; RanBP2-like 3; RanBP2L3 (RGPD8, RANBP2ALPHA, RANBP2L3)
Function:
1) transport factor
2) Ran-GTP mediated protein import
3) one of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere
Structure:
- contains 1 GRIP domain
- contains 2 RanBD1 domains
- contains 3 TPR repeats
Compartment: nuclear pore complex
General
phosphoprotein
Ran-binding protein 2-like (RanBP2L)
Properties
SIZE: entity length = 1765 aa
MW = 199 kD
COMPARTMENT: cell nucleus
MOTIF: tetratricopeptide repeat {26-59}
tetratricopeptide repeat {60-93}
tetratricopeptide repeat {648-681}
Thr phosphorylation site {T1029}
Ser phosphorylation site {S1032}
Ran binding domain type 1 {1036-1172}
serine-rich region {1261-1266}
MOTIF: serine residue (SEVERAL)
Ran binding domain type 1 {1333-1469}
Ser phosphorylation site {S1478}
Ser phosphorylation site {S1534}
GRIP {1702-1752}
Database Correlations
OMIM 602752
UniProt O14715
PFAM correlations
Entrez Gene 727851
Kegg hsa:727851
References
UniProt :accession O14715