radical S-adenosyl methionine domain-containing protein 1, mitochondrial (oxygen-independent coproporphyrinogen III oxidase-like protein RSAD1, RSAD1)

Function: - may be involved in porphyrin cofactor biosynthesis Cofactor: - binds 1 4Fe-4S cluster - cluster is coordinated with 3 cysteines & an exchangeable S-adenosyl-L-methionine (putative) Structure: - belongs to the anaerobic coproporphyrinogen III oxidase family Compartment: mitochondria (putative)

General

metalloprotein mitochondrial protein oxidoreductase

Properties

SIZE: MW = 49 kD entity length = 442 aa COMPARTMENT: mitochondria MOTIF: alanine-rich region {12-18} MOTIF: alanine residue (SEVERAL) arginine-rich region {20-23} MOTIF: arginine residue (SEVERAL) binding site SITE: 43-43 FOR-BINDING-OF: S-adenosylmethionine cofactor-binding site [49-49] COFACTOR-BOUND: iron sulfur [FeS] cluster cofactor-binding site [53-53] COFACTOR-BOUND: iron sulfur [FeS] cluster binding site SITE: 55-55 FOR-BINDING-OF: S-adenosylmethionine cofactor-binding site [56-56] COFACTOR-BOUND: iron sulfur [FeS] cluster binding site SITE: 98-98 FOR-BINDING-OF: S-adenosylmethionine S-adenosyl-L-methionine 2 binding {99-100} binding site SITE: 131-131 FOR-BINDING-OF: S-adenosylmethionine binding site SITE: 158-158 FOR-BINDING-OF: S-adenosylmethionine binding site SITE: 170-170 FOR-BINDING-OF: S-adenosylmethionine binding site SITE: 195-195 FOR-BINDING-OF: S-adenosylmethionine

Database Correlations

UniProt Q9HA92 PFAM correlations

References

UniProt :accession Q9HA92