RAD51-associated protein 1 (RAD51-interacting protein, RAD51AP1, PIR51)

Function: 1) role in DNA damage response pathway associated with activation of homologous recombination & DNA double-strand break repair 2) binds to single & double stranded DNA 3) capable of aggregating DNA 4) binds RNA 5) isoform 2 interacts with RAD51 Compartment: - nucleus - colocalizes with RAD51 to multiple nuclear foci Alternative splicing: named isoforms=3 Expression: 1) highly expressed in testis & thymus 2) lower levels in colon & small intestine 3) little or no expression in spleen, prostate, ovary, peripheral blood leukocytes

Properties

SIZE: MW = 38 kD entity length = 352 aa COMPARTMENT: cell nucleus

Database Correlations

OMIM 603070 UniProt Q96B01

References

UniProt :accession Q96B01