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RABGEF1/RABEP1 complex
Function:
- binds RAB4A & RAB5A (activated by GTP-binding)
Structure:
- heterodimer of RABGEF1 & RABEP1
General
molecular complex
Properties
SUBUNITS: Rab5 GDP/GTP exchange factor
COMPARTMENT: cytoplasm
MOTIF: ubiquitinated proteins interaction {139-252}
MOTIF: Zinc finger
NAME: Zinc finger
SITE: 151-185
EFFECTOR-BOUND: Zn+2
Ser phosphorylation site {S302}
Ser phosphorylation site {S310}
VPS9 {449-592}
Ser phosphorylation site {S617}
coiled coil {624-665}
Rab GTPase-binding effector protein 1
COMPARTMENT: cytoplasm
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
coiled coil {11-345}
Ser phosphorylation site {S407}
Thr phosphorylation site {T408}
Ser phosphorylation site {S410}
coiled coil {534-816}
References
UniProt :accession Q9UJ41
Components
Rab GTPase-binding effector protein 1; rabaptin-4; rabaptin-5; rabaptin-5alpha; renal carcinoma antigen NY-REN-17 (RABEP1, RAB5EP, RABPT5, RABPT5A)
Rab5 GDP/GTP exchange factor; RAP1; Rabaptin-5-associated exchange factor for Rab5; Rabex-5 (RABGEF1, RABEX5)