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purified protein derivative (PPD, Tubersol)

Indications: 1) skin test in the diagnosis of tuberculosis 2) aid in assessment of cell-mediated immunity Contraindications: - NOT contraindicated for BCG-vaccinated patients Procedure: (also see tuberculin skin testing) - 5 TU intradermally - Read 48-72 hours later - 250 TU if no response to 5 TU Injection: 1 TU/0.1 mL (1 mL), 5 TU/0.1 mL (1 mL, 5 mL), 250 TU/0.1 mL (1 mL) Elimination: liver pregnancy-category C safety in lactation +

Related

Mycobacterium tuberculosis (MTB) tuberculin-skin testing (TST)

General

pharmacologic combination antigen

References

  1. Diagnostic History & Physical Examination in Medicine, Chan & Winkle, Current Clinical Strategies, Laguna Hills, CA 1996
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  3. Department of Veterans Affairs, VA National Formulary
  4. Medical Knowledge Self Assessment Program (MKSAP) 14, American College of Physicians, Philadelphia 2006