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PSO4 complex
Function:
- complex required in the DNA interstrand cross-link repair process
Structure: subunits: PRPF19, CDC5L, PLRG1
Compartment: nucleus
General
molecular complex
Properties
SUBUNITS: pre-mRNA-processing factor 19
COMPARTMENT: cell nucleus
MOTIF: U-box {1-68}
WD repeat {219-259}
WD repeat {262-301}
WD repeat {304-345}
WD repeat {348-387}
WD repeat {390-429}
WD repeat {433-472}
WD repeat {473-503}
cell division cycle 5-like protein
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: HTH myb-type 1 {1-56}
MOTIF: DNA-binding motif
SITE: 31-54
HTH myb-type 2 {57-108}
MOTIF: DNA-binding motif
SITE: 82-104
coiled coil {142-245}
MOTIF: Thr phosphorylation site {T227}
PPP1R8 interaction {260-606}
MOTIF: Ser phosphorylation site {S303}
Ser phosphorylation site {S317}
Thr phosphorylation site {T377}
Thr phosphorylation site {T385}
Thr phosphorylation site {T396}
breakpoint {414}
Thr phosphorylation site {T415}
Thr phosphorylation site {T424}
Thr phosphorylation site {T429}
Thr phosphorylation site {T430}
Ser phosphorylation site {S437}
Thr phosphorylation site {T438}
Thr phosphorylation site {T442}
DAPK3 interaction {501-659}
coiled coil {676-701}
PLRG1 interaction {706-800}
coiled coil {764-802}
pleiotropic regulator 1
COMPARTMENT: cell nucleus
MOTIF: WD repeat {202-241}
WD repeat {244-283}
WD repeat {286-325}
WD repeat {328-367}
WD repeat {370-410}
WD repeat {411-449}
WD repeat {460-499}
References
UniProt :accession Q9UGP8
Components
cell division cycle 5-like protein; Cdc5-like protein; Pombe cdc5-related protein (CDC5L, KIAA0432, PCDC5RP)
pleiotropic regulator 1 (PLRG1)
pre-mRNA-processing factor 19 (PRP19/PSO4 homolog, hPso4, nuclear matrix protein 200, senescence evasion factor, PRPF19, NMP200, PRP19, SNEV)