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proto-oncogene

cellular counterpart of viral oncogenes involved in normal cell function; mutation, abnormal activation or overexpression of these genes may be associated with tumor formation.

Related

oncogene or viral oncogene proto oncogene protein

Specific

abl proto-oncogene AF4 gene or MLLT2 gene AF6 gene or MLLT4 gene AF9 gene or MLLT3 gene AFX1 gene or MLLT7 gene akt proto-oncogene ALL1-related (ALR) gene or MLL2 gene AML1 or CBFA2 gene arg proto-oncogene or abl-L (abl-like) proto-oncogene arh proto-oncogene or rho proto-oncogene ATF1 gene bcl-2 proto-oncogene bcl-x proto-oncogene bcl3 gene bic proto-oncogene bim-1 proto-oncogene blym1 proto-oncogene or blym proto-oncogene Cain gene cbl proto-oncogene cbl-2 proto-oncogene CCND2 CCND3 gene CCNG1 clathrin assembly lymphoid-myeloid leukemia (CALM) gene cot proto-oncogene crk proto-oncogene dbl/MCF2 proto-oncogene egr1 proto-oncogene, early growth response-1 gene, TIS8, KROX-24, zif-268 or NGF1A eleven-nineteen leukemia (ENL) gene erb proto-oncogene ets proto-oncogene evi-1 proto-oncogene EWS gene fibroblast growth factor-5 [FGF5] proto-oncogene fms proto-oncogene fos family proto-oncogene fps/fes (Fujimani poultry sarcoma/feline sarcoma) proto-oncogene fra1 proto-oncogene Friend leukemia virus integration-1 (fli1) or Sic1 gene fur proto-oncogene gip proto-oncogene gli family proto-oncogene gsp proto-oncogene (GNAS1) hematopoietic stem cell leukemia [SCL] gene, tal1 or TCL5 HLM2 proto-oncogene or Endogenous retroviral pol gene-like sequence 1 (ERPL1) homeobox 2.4 gene (hox-2.4) hst proto-oncogene; ks3 proto-oncogene int2 proto-oncogene jun family proto-oncogene kit proto-oncogene or white spotting locus [W] gene LCA liver cancer proto-oncogene lyl-1 proto-oncogene maf proto-oncogene mas proto-oncogene or mas1 proto-oncogene mdm2 proto-oncogene met proto-oncogene mim1 proto-oncogene mos proto-oncogene myb proto-oncogene myc proto-oncogene myeloid/lymphoid, or mixed lineage, leukemia (MLL) gene, TRX1 gene, trithorax homolog, HRX gene or ALL1 gene Notch1 proto-oncogene papillary thyroid carcinoma [PTC] gene parathyroid adenomatosis [PRAD]-1 gene, CCND1 or bcl-1 pbx proto-oncogene pim-1 proto-oncogene rab proto-oncogene raf proto-oncogene ral proto-oncogene rap proto-oncogene ras proto-oncogene RCK proto-oncogene (DDX6, HLR2) rel proto-oncogene ret proto-oncogene ros proto-oncogene, ros1 proto-oncogene or mcf1 proto-oncogene sea proto-oncogene sil proto-oncogene or SCL-interrupting locus gene sis proto-oncogene ski proto-oncogene src proto-oncogene family suppressor of variegation, enhancer of zeste & Trithorax (SET) gene tax proto-oncogene thrombopoietin receptor or myeloproliferative leukemia (MPL) gene tropomyosin receptor kinase [trk] proto-oncogene family vav proto-oncogene vav2 proto-oncogene wnt family proto-oncogene

General

gene

Properties

MOTIF: transcription factor binding site transcriptional start site exon intron transcriptional termination site

References

Lewin, genes VII. Oxford University Press 2000