protein tyrosine phosphatase 4, non-receptor type; protein-tyrosine phosphatase MEG1; PTPase-MEG1 (MEG, PTPN4)

Function: - protein tyrosine phosphatase - may act at junctions between the membrane & the cytoskeleton Structure: - belongs to the protein-tyrosine phosphatase family non-receptor class subfamily - contains 1 FERM domain - contains 1 PDZ domain (DHR domain) - contains 1 tyrosine-protein phosphatase domain

General

cytoskeletal protein tyrosine phosphatase, non-receptor type

Properties

SIZE: entity length = 926 aa MW = 106 kD COMPARTMENT: cytoplasm MOTIF: FERM domain NAME: FERM domain SITE: 29-312 PDZ domain NAME: PDZ domain SITE: 517-589 Tyrosine-protein phosphatase {655-911} MOTIF: cysteine residue {C852} STATE: active state

Database Correlations

OMIM 176878 UniProt P29074 PFAM correlations Entrez Gene 5775 Kegg hsa:5775 ENZYME 3.1.3.48

References

UniProt :accession P29074