protein-tyrosine phosphatase-like member B (PTPLB)

Function: - probable anti-phosphatase (putative) - interacts with BCAP31 Structure: - belongs to the PTPLA family - shares some similarity with tyrosine phosphatase proteins but it has probably no phosphatase activity Compartment: - endoplasmic reticulum membrane Expression: - expressed in testis, spleen, prostate, colon & heart > thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle & pancreas > kidney, placenta, brain & lung - turns over rapidly through degradation by the proteasome system

General

glycoprotein membrane protein

Properties

SIZE: entity length = 254 aa MW = 28 kD COMPARTMENT: endoplasmic reticulum MOTIF: glycine-rich region {12-18} transmembrane domain {41-61} transmembrane domain {86-106} transmembrane domain {134-154} transmembrane domain {171-191} N-glycosylation site {N209} transmembrane domain {217-237}

Database Correlations

UniProt Q6Y1H2 Pfam PF04387 Kegg hsa:2015

References

UniProt :accession Q6Y1H2