protein-tyrosine phosphatase-like member A; Cementum attachment protein (PTPLA)

Function: - probable anti-phosphatase - may have role in development, differentiation, & maintenance of different tissue types - may play role in myogenesis & cardiogenesis Structure: - belongs to the PTPLA family - shares some similarity with tyrosine phosphatase proteins but probably has no phosphatase activity Compartment: membrane (putative) Alternative splicing: named isoforms=2 Expression: - highly expressed in the myocardium, & to a lesser extent in skeletal & smooth muscular tissues including those from stomach, jejunum, & bladder - expressed in fetal heart

General

glycoprotein membrane protein

Properties

SIZE: entity length = 288 aa MW = 32 kD COMPARTMENT: cellular membrane MOTIF: transmembrane domain {75-95} transmembrane domain {120-140} transmembrane domain {205-225} N-glycosylation site {N243} transmembrane domain {251-271}

Database Correlations

UniProt B0YJ81 Pfam PF04387 Kegg hsa:9200

References

UniProt :accession B0YJ81