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protein tyrosine phosphatase 3, non-receptor type; protein tyrosine phosphatase H1 (PTPN3, PTP-H1, PTPH1)
Function:
- protein tyrosine phosphatase
- may act at junctions between the membrane & the cytoskeleton
Structure:
- belongs to the protein-tyrosine phosphatase family non-receptor class subfamily
- contains 1 FERM domain
- contains 1 PDZ domain (DHR domain)
- contains 1 tyrosine-protein phosphatase domain
Compartment: cytoplasm
General
cytoskeletal protein
tyrosine phosphatase, non-receptor type
Properties
SIZE: entity length = 913 aa
MW = 104 kD
COMPARTMENT: cytoplasm
MOTIF: FERM domain
NAME: FERM domain
SITE: 29-312
PDZ domain
NAME: PDZ domain
SITE: 510-582
Tyrosine-protein phosphatase {646-901}
MOTIF: cysteine residue {C842}
STATE: active state
Database Correlations
OMIM 176877
UniProt P26045
PFAM correlations
Entrez Gene 5774
Kegg hsa:5774
ENZYME 3.1.3.48
References
UniProt :accession P26045