protein transport protein SEC61

Function: - protein translocation in the endoplasmic reticulum - insertion of secretory & membrane polypeptides into ER - assembly of membrane & secretory proteins - tightly associated with membrane-bound ribosomes, either directly or through adapter proteins Subunits: - SEC61-alpha, SEC61-beta & SEC61-gamma Compartment: endoplasmic reticulum

General

carrier protein (transporter) membrane protein molecular complex

Properties

COMPARTMENT: cellular membrane MOTIF: membrane region SUBUNITS: transport protein sec61-alpha COMPARTMENT: endoplasmic reticulum MOTIF: cytoplasmic domain {2-33} transmembrane domain {34-53} exoplasmic loop {54-76} transmembrane domain {77-96} cytoplasmic loop {97-117} transmembrane domain {118-138} exoplasmic loop {139-144} transmembrane domain {145-165} cytoplasmic loop {166-172} transmembrane domain {173-193} exoplasmic loop {194-240} transmembrane domain {241-261} cytoplasmic loop {262-288} transmembrane domain {289-309} exoplasmic loop {310-354} transmembrane domain {355-375} cytoplasmic loop {376-420} transmembrane domain {421-441} exoplasmic loop {442-445} transmembrane domain {446-462} cytoplasmic domain {463-476} transport protein sec61-beta COMPARTMENT: endoplasmic reticulum MOTIF: Ser phosphorylation site {S13} Ser phosphorylation site {S14} Ser phosphorylation site {S17} Ser phosphorylation site {S19} Ser phosphorylation site {S29} Thr phosphorylation site {T30} transmembrane domain {71-91} transport protein SEC61 subunit gamma COMPARTMENT: endoplasmic reticulum MOTIF: transmembrane domain {33-61}

References

UniProt :accession P38391

Components

transport protein SEC61 subunit gamma (SEC61G) transport protein sec61-alpha (SEC61A) transport protein sec61-beta (SEC61B)