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Protein strawberry notch homolog 2 (SBNO2, KIAA0963)
Function:
- seems to have transcriptional repression activity in macrophages
Structure: belongs to the SBNO family
Alternative splicing: named isoforms=2
Expression:
- detected in macrophages
- IL10 regulates expression (STAT3-dependent)
General
transcriptional silencer (transcriptional repressor)
Properties
SIZE: entity length = 1366 aa
MW = 150 kD
COMPARTMENT: cell nucleus
MOTIF: glutamate-rich region {183-195}
MOTIF: glutamate residue (SEVERAL)
proline-rich region
SITE: 1234-1294
MOTIF: proline residue (SEVERAL)
Database Correlations
UniProt Q9Y2G9
Kegg hsa:2290
References
UniProt :accession Q9Y2G9