protein reprimo (RPRM)

Function: - may be involved in the regulation of p53-dependent G2 arrest of the cell cycle - seems to induce cell cycle arrest by inhibiting CDC2 activity & nuclear translocation of the CDC2 cyclin B1 complex (putative) Structure: belongs to the reprimo family Compartment: cytoplasm, membrane Expression: induced by TP53/p53, following X-ray irradiation Note: 'reprimo' signifies stop/repress

General

glycoprotein membrane protein

Properties

SIZE: entity length = 109 aa MW = 12 kD COMPARTMENT: cytoplasm MOTIF: N-glycosylation site {N7} N-glycosylation site {N18} transmembrane domain {56-76}

References

UniProt :accession Q9NS64