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protein CARP; dermal papilla-derived protein 5 (CARP, FAM188A, C10orf97, DERP5, MSTP126, My042)
Function:
- may have pro-apoptotic function
- overexpression significantly inhibits cell proliferation in several tumor cell lines
Structure: belongs to the CARP family
Compartment: nucleus
Alternative splicing: named isoforms=2
Expression:
- highly expressed in heart, skeletal muscle, & kidney
- weak expression in liver & brain
Note:
- named CARP for 'CARD domain-containing protein' [2]
- however, no CARD domain is detected by any prediction tool
General
nuclear protein
phosphoprotein
Properties
SIZE: entity length = 445 aa
MW = 50 kD
COMPARTMENT: cell nucleus
MOTIF: Ser phosphorylation site {S125}
Database Correlations
UniProt Q9H8M7
Kegg hsa:8001
References
- UniProt :accession Q9H8M7
- PMID: 12054670