protein APCDD1; adenomatosis polyposis coli down-regulated 1 protein (APCDD1, DRAPC1, FP7019)

Function: - developmental target gene of the Wnt (Beta-catenin) pathway Compartment: membrane Expression: - expressed in heart, pancreas, prostate, ovary > lung, liver, kidney, spleen, thymus, colon, peripheral lymphocytes - transcriptionally regulated by the CTNNB1/TF7L2 complex Pathology: - role in colorectal carcinoma

General

glycoprotein membrane protein

Properties

SIZE: MW = 59 kD entity length = 514 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-26} N-glycosylation site {N168} transmembrane domain {493-512}

Database Correlations

OMIM 607479 UniProt Q8J025

References

UniProt :accession Q8J025