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prosopagnosia; face blindness, facial agnosia
Etiology:
- neurodegenerative disease
- posterior cortical atrophy (21%)
- primary prosopagnosia syndrome (21%)
- Alzheimer's disease (16%)
- non-degenerative diseases
- primary brain tumors (40%)
- ischemic stroke or hemorrhagic stroke (12%)
- epilepsy (12%).
- migraine
- posterior reversible encephalopathy syndrome
- delirium
- hypoxic encephalopathy
- genetic disease
- Niemann-Pick disease type C
Pathology:
- a neurological disorder
- damage or impairment of the right fusiform gyrus
- temporal lobe & occipital lobes & connecting fusiform gyrus are key brain areas involved [4]
Clinical manifestations:
- face blindness or facial agnosia
- inability to recognize faces
- loss of facial recognition in adulthood is not always permanent [4]
Management:
- prognosis:
- improvement or resolution may occur with
- posterior reversible encephalopathy syndrome
- delirium
- hypoxic encephalopathy
- ischemic stroke
General
sign/symptom
References
- Kieseler ML, Duchaine B
Persistent prosopagnosia following COVID-19.
Cortex, 2023. March 9
https://www.sciencedirect.com/science/article/pii/S0010945223000448
- National Institute of Neurological Disorders and Stroke
Prosopagnosia
https://www.ninds.nih.gov/health-information/disorders/prosopagnosia
- Wikipedia: Prosopagnosia
https://en.wikipedia.org/wiki/Prosopagnosia
- George J
Face Blindness Is Not Always Permanent.
Largest study to date looks at inability to recognize familiar faces.
MedPage Today January 12, 2024
https://www.medpagetoday.com/neurology/generalneurology/10824
- Josephs KA, Josephs KA.
Prosopagnosia: face blindness and its association with neurological disorders.
Brain Communications. 2024. Jan 5
PMID: 38419734 PMCID: PMC10901275 Free PMC article
https://academic.oup.com/braincomms/advance-article/doi/10.1093/braincomms/fcae002/7511329