proliferation-associated nuclear element protein 1: centromere protein M; CENP-M; interphase centromere complex protein 39 (CENPM, C22orf18, ICEN39, PANE1)

Function: - component of the CENPA-NAC complex Compartment: - nucleus, cytoplasm, chromosome, centromere, kinetochore - nuclear in non-confluent cells - cytoplasmic in confluent or dividing cells (putative) - localizes in the kinetochore domain of centromeres Alternative splicing: named isoforms=3 Expression: - isoform 3 is expressed in: a) spleen > heart, prostate, ovary b) resting CD19 B-cells c) B-lineage chronic lymphocytic leukemia (B-CLL) cells d) activated B-cells (weakly expressed) - isoform 1 is expressed in: a) activated CD19 cells b) resting CD19 B-cells (weakly expressed)

Properties

SIZE: entity length = 180 aa MW = 20 kD COMPARTMENT: cytoplasm cell nucleus

Database Correlations

OMIM 610152 UniProt Q9NSP4 Pfam PF11111 Entrez Gene 79019 Kegg hsa:79019

References

UniProt :accession Q9NSP4