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profilactin
Function:
- ties up G-actin in form that will only bind + end of F-actin
Structure:
- subunits: profilin, G-actin
Interactions
molecular events
General
cytoskeletal protein
molecular complex
Properties
COMPARTMENT: cytoplasm
SUBUNITS: profilin
MOTIF: phosphorylation site
binding site
FOR-BINDING-OF: phosphatidylinositol-4-phosphate
G-actin
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
Tyr phosphorylation site {Y53}
Tyr phosphorylation site {Y91}
Tyr phosphorylation site {Y166}
Tyr phosphorylation site {Y169}
Tyr phosphorylation site {Y198}
Tyr phosphorylation site {Y218}
adenine nucleotide-binding site
EFFECTOR-BOUND: adenosine triphosphate
Tyr phosphorylation site {Y294}
Thr phosphorylation site {T318}
References
Molecular Cell Biology (2nd ed) Darnell J; Lodish H
& Baltimore D (eds), Scientific American Books,
WH Freeman, NY 1990, pg 886
Components
G-actin
profilin