proactivator polypeptide-like 1 [Contains: Saposin A-like; Saposin B-Val-like; Saposin B-like; Saposin C-like; Saposin D-like] (PSAPL1)

Function: - may activate the lysosomal degradation of sphingolipids Structure: - contains 2 saposin A-type domains - contains 4 saposin B-type domains Compartment: secreted

Properties

SIZE: MW = 57 kD entity length = 521 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-17} Saposin A-type 1 {19-59} Saposin B-type 1 {60-144} MOTIF: cysteine residue {C64} MODIFICATION: cysteine residue {C140} cysteine residue {C67} MODIFICATION: cysteine residue {C134} cysteine residue {C95} MODIFICATION: cysteine residue {C107} cysteine residue {C107} MODIFICATION: cysteine residue {C95} cysteine residue {C134} MODIFICATION: cysteine residue {C67} cysteine residue {C140} MODIFICATION: cysteine residue {C64} Saposin B-type 2 {180-258} MOTIF: cysteine residue {C184} MODIFICATION: cysteine residue {C254} cysteine residue {C187} MODIFICATION: cysteine residue {C248} N-glycosylation site {N201} cysteine residue {C213} MODIFICATION: cysteine residue {C224} cysteine residue {C224} MODIFICATION: cysteine residue {C213} cysteine residue {C248} MODIFICATION: cysteine residue {C187} cysteine residue {C254} MODIFICATION: cysteine residue {C184} Saposin B-type 3 {290-370} MOTIF: cysteine residue {C294} MODIFICATION: cysteine residue {C366} cysteine residue {C297} MODIFICATION: cysteine residue {C360} N-glycosylation site {N311} cysteine residue {C325} MODIFICATION: cysteine residue {C336} cysteine residue {C336} MODIFICATION: cysteine residue {C325} cysteine residue {C360} MODIFICATION: cysteine residue {C297} cysteine residue {C366} MODIFICATION: cysteine residue {C294} Saposin B-type 4 {392-473} MOTIF: cysteine residue {C396} MODIFICATION: cysteine residue {C469} cysteine residue {C399} MODIFICATION: cysteine residue {C463} cysteine residue {C427} MODIFICATION: cysteine residue {C438} cysteine residue {C438} MODIFICATION: cysteine residue {C427} cysteine residue {C463} MODIFICATION: cysteine residue {C399} cysteine residue {C469} MODIFICATION: cysteine residue {C396} Saposin A-type 2 {475-515}

Database Correlations

UniProt Q6NUJ1 PFAM correlations

References

UniProt :accession Q6NUJ1