Search
primer
A molecule, often a small polymer, that initiates synthesis of a larger molecule.
In molecular biology:
DNA polymerase is dependent upon a small oligonucleotides as a primer to initiate replication. These primers are complementary & hydrogen-bonded to a sequence on the DNA strand to be replicated, resulting in a short segment of double-stranded DNA or DNA-RNA in the case of reverse transcriptase.
General
biochemistry
References
Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999