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pre-mRNA-processing factor 6 (PRP6 homolog, U5 snRNP-associated 102 kD protein, U5-102 kD protein, PRPF6, C20orf14)
Function:
- role pre-mRNA splicing
- may act in the tri-snRNP complex as a bridging factor between U5 & U4/U6 snRNPs in the late step of spliceosome assembly
- may be necessary for tri-snRNP formation
- associates with U5 snRNP particle
- associates with U4/U6 snRNP particle
- identified in the spliceosome C complex
Structure: contains 9 HAT repeats
Compartment: nucleus
General
nuclear protein
Properties
SIZE: MW = 107 kD
entity length = 941 aa
COMPARTMENT: cell nucleus
MOTIF: HAT {384-416}
HAT {418-444}
HAT {445-476}
HAT {554-586}
HAT {588-620}
HAT {622-654}
HAT {689-721}
HAT {723-755}
HAT {855-887}
Database Correlations
UniProt O94906
PFAM correlations
References
UniProt :accession O94906
Component-of
spliceosome C complex