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pregnanediol in 24 hour urine
Indications:
- evaluation of
- pregnancy
- placental insufficiency
- pre-eclampsia
- precocious puberty
- congenital adrenal hyperplasia
- growth hormone-secreting pituitary adenoma
- granulosa theca cell tumors
- arrhenoblastoma
- chorioepithelioma
- luteal cyst
- ovarian failure
Reference interval:
- < 0.1 mg/day 0-2 years
- < 0.3 mg/day 3-5 years
- < 0.6 mg/day 6-9 years
- < 0.7 mg/day 10-15 years male
- < 1.3 mg/day 10-15 years female
- < 1.9 mg/day adult male
- < 2.6 mg/day adult female (follicular phase)
- < 10.6 mg/day adult female (luteal phase)
- 10-35 mg/day pregnant female 1st trimester
- 35-70 mg/day pregnant female 2nd trimester
- 70-100 mg/day pregnant female 3rd trimester
Increases:
- precocious puberty
- growth hormone-secreting pituitary adenoma
- chorioepithelioma
- congenital adrenal hyperplasia caused by steroid 17-alpha hydroxylase deficiency & steroid 11-beta hydroxylase deficiency
- granulosa theca cell tumors
- luteal cyst
- arrhenoblastoma
Decreases:
- placental insufficiency
- pre-eclampsia
- ovarian failure
Related
pregnanediol
General
24 hour urine
pregnanediol in urine
References
- Clinical Guide to Laboratory Tests, 4th edition, HB Wu ed,
WB Saunders, Philadelphia, 2006