prednisolone/sulfacetamide (Blephamide, Cetapred, Metimyd)

Tradenames: Blephamide, Cetapred, Metimyd. Indications: - inflammatory ocular condition with risk of infection - eyelid disease - may also be used as on otic solution Contraindications: sulfa allergy Dosage: 1) suspension: instil 1-3 drops every 2-3 hours while awake 2) ointment: apply QD-QID Blephamide: (ophthalmic) - sodium sulfacetamide 10%/prednisolone acetic_acid 0.2% (3.5 g [ointment], 5 mL, 10 mL [solution]) Cetapred: (ophthalmic) - sodium sulfacetamide 10%/prednisolone acetic_acid 0.25% (3.5 g [ointment]) Adverse effects: (ophthalmic) 1) not common (1-10%) - local burning, stinging, irritation 2) uncommon (< 1%) - vertigo, seizures, psychosis, pseudotumor cerebri, headache, Stevens-Johnson syndrome, skin atrophy, Cushing's syndrome, pituitary-adrenal axis suppression, peptic ulcer, nausea/vomiting, muscle weakness, osteoporosis, fractures, cataracts, glaucoma Mechanism of action: - antibiotic/steroid combination

References

Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998

Components

prednisolone; deltahydrocortisone; metacortandralone (Pred Forte, AK-Pred, Inflamase, Pediapred, Pred Mild, Prelone, Flo-Pred, Veripred 20) sulfacetamide (Sulfacet)