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postpartum hemolytic uremic syndrome (HUS)
Also postpartum acute renal failure.
Etiology: retained placenta?
Epidemiology: rare
Clinical manifestations:
1) occurs days to 10 weeks postpartum, generally 3-6 weeks
2) oliguria
3) severe hypertension
Laboratory:
1) CBC with peripheral smear
a) microangiopathic hemolytic anemia
b) thrombocytopenia
2) renal function tests
a) oliguria
b) uremia
Management:
1) dilatation & curettage
2) supportive therapy
3) fresh frozen plasma
4) anti-platelet therapy?
5) plasma exchange has been used
6) renal failure often persists in survivors
General
hemolytic uremic syndrome (HUS)
complications of the puerperium
References
- Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 619-20
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998