porimin (transmembrane protein 123, pro-oncosis receptor inducing membrane injury, keratinocytes-associated transmembrane protein 3, KCT-3, TMEM123, KCT3, PSEC0111, UNQ641/PRO1271)

Function: - role in oncosis (oncotic cell death) Structure: - belongs to the CD164 family Compartment: membrane Alternative splicing: named isoforms=2 Expression: - ubiquitous - not expressed in ovary - expressed in keratinocytes

General

glycoprotein membrane protein

Properties

SIZE: MW = 22 kD entity length = 208 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-26} N-glycosylation site {N46} N-glycosylation site {N50} threonine-rich region {52-153} MOTIF: threonine residue (SEVERAL) N-glycosylation site {N64} N-glycosylation site {N68} N-glycosylation site {N83} N-glycosylation site {N96} N-glycosylation site {N106} N-glycosylation site {N124} N-glycosylation site {N138} transmembrane domain {167-187}

Database Correlations

OMIM 606356 UniProt Q8N131

References

UniProt :accession Q8N131