poly(A) polymerase beta; PAP-beta; polynucleotide adenylyltransferase beta; testis-specific poly(A) polymerase (PAPOLB PAPT)

Function: - DNA polymerase - interacts with GSG1 (putative) Cofactor: - binds 2 Mg⁺² - also active with Mn+2 Structure: belongs to the poly(A) polymerase family Compartment: nucleus Expression: testis specific

General

DNA polymerase nuclear protein testis-specific protein

Properties

SIZE: entity length = 636 aa MW = 72 kD COMPARTMENT: cell nucleus MOTIF: ATP-binding site NAME: ATP-binding site SITE: 100-102 ATP-binding site NAME: ATP-binding site SITE: 109-109 ATP-binding site NAME: ATP-binding site SITE: 113-115 MOTIF: Mg+2-binding site SITE: 113-113 Mg+2-binding site SITE: 115-115 phenylalanine residue {153} lysine residue {158} Mg+2-binding site SITE: 167-167 MOTIF: ATP-binding site NAME: ATP-binding site SITE: 167-167 ATP-binding site NAME: ATP-binding site SITE: 228-228 ATP-binding site NAME: ATP-binding site SITE: 237-237 ATP-binding site NAME: ATP-binding site SITE: 246-247 asparagine residue {328} arginine residue {399} aspartate residue {524}

Database Correlations

OMIM 607436 UniProt Q9NRJ5 PFAM correlations Entrez Gene 56903 Kegg hsa:56903 ENZYME 2.7.7.19

References

UniProt :accession Q9NRJ5