polycomb group protein (PcG)

Function: 1) form multiprotein complexes (see Polycomb group multiprotein PRC1 complex) 2) transcriptional repression of genes via modification of chromatin, rendering it heritably changed in expressibility 3) maintain transcriptionally repressive state of homeotic genes throughout development 4) NOT required to initiate repression, but to maintain it during later stages of development 5) methylation of histones, rendering chromatin heritably changed in its expressibility (putative)

Specific

lethal[3]malignant brain tumor-like protein; L[3]mbt-like; L[3]mbt protein homolog; H-l[3]mbt protein; H-L[3]MBT (L3MBTL1, L3MBTL, KIAA0681, L3MBT) polycomb group protein ASXL1 (additional sex combs-like protein 1, ASXL1, KIAA0978) polycomb group protein ASXL3 (additional sex combs-like protein 3, ASXL3, KIAA1713) polycomb protein EED; hEED; WD protein associating with integrin cytoplasmic tails 1; WAIT-1 (EED) sex comb on midleg-like protein 1 (SCML1) sex comb on midleg-like protein 2 (SCML2)

References

UniProt :accession Q9Y468, Q15022