polyadenylate-binding protein 3; poly(A)-binding protein 3; PABP 3; testis-specific poly(A)-binding protein (PABPC3, PABP3, PABPL3)

Function: - binds the poly(A) tail of mRNA - may be involved in cytoplasmic regulatory processes of mRNA metabolism - binds poly(A) with a slightly lower affinity as compared to PABPC1 Structure: - belongs to the polyadenylate-binding protein type-1 family - contains 1 PABC domain - contains 4 RRM domain (RNA recognition motif)s Compartment: cytoplasm (putative) Expression: testis specific

General

polyadenylate binding protein testis-specific protein

Properties

SIZE: entity length = 631 aa MW = 70 kD COMPARTMENT: cytoplasm MOTIF: RNP motif NAME: RNP motif SITE: 11-89 FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif NAME: ribonucleoprotein-1 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif ribonucleoprotein-2 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif RNP motif NAME: RNP motif SITE: 99-175 FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif NAME: ribonucleoprotein-1 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif ribonucleoprotein-2 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif RNP motif NAME: RNP motif SITE: 191-268 FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif NAME: ribonucleoprotein-1 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif ribonucleoprotein-2 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif RNP motif NAME: RNP motif SITE: 294-370 FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif NAME: ribonucleoprotein-1 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif ribonucleoprotein-2 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif PABC {537-614}

Database Correlations

OMIM 604680 UniProt Q9H361 PFAM correlations Entrez Gene 5042 Kegg hsa:5042

References

UniProt :accession Q9H361