plexin domain-containing protein 2 (tumor endothelial marker 7-related protein, PLXDC2, TEM7R, UNQ2514/PRO6003)

Function: 1) role in tumor angiogenesis 2) interacts with CTTN Structure: 1) belongs to the plexin family 2) contains 1 PSI domain Compartment: membrane Alternative splicing: named isoforms=3 Expression: - expressed in endothelial cells of colonic stroma

General

glycoprotein membrane protein

Properties

SIZE: MW = 60 kD entity length = 529 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-30} N-glycosylation site {N103} N-glycosylation site {N160} PSI {327-372} threonine-rich region {383-427} MOTIF: threonine residue (SEVERAL) transmembrane domain {455-475}

Database Correlations

OMIM 606827 UniProt Q6UX71 Pfam PF01437

References

UniProt :accession Q6UX71