plexin-B3 (PLXNB3 KIAA1206 PLXN6)

Function: - receptor for SEMA5A. - plays a role in axon guidance, invasive growth & cell migration - binds c-MET & MST1R Structure: - belongs to the plexin family - contains 4 IPT/TIG domains - contains 1 Sema domain Compartment: membrane Expression: - detected at very low levels in several fetal tissues

General

glycoprotein plexin B

Properties

SIZE: entity length = 1909 aa MW = 207 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-44} Sema {45-471} MOTIF: N-glycosylation site {N51} N-glycosylation site {N231} N-glycosylation site {N615} N-glycosylation site {N802} IPT/TIG 1 {835-925} MOTIF: N-glycosylation site {N900} IPT/TIG 2 {927-1012} MOTIF: N-glycosylation site {N957} IPT/TIG 3 {1015-1145} MOTIF: N-glycosylation site {N1101} IPT/TIG 4 {1159-1244} MOTIF: N-glycosylation site {N1218} transmembrane domain {1256-1276}

Database Correlations

OMIM 300214 UniProt Q9ULL4 PFAM correlations Entrez Gene 5365 Kegg hsa:5365

References

UniProt :accession Q9ULL4