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plexin-A3; plexin-4; Semaphorin receptor SEX (PLXNA3 PLXN4 SEX)

Function: - putative receptor involved in the development of neural & epithelial tissues Structure: - belongs to the plexin family - contains 4 IPT/TIG domains - contains 1 Sema domain Compartment: membrane Expression: - predominant in neural tissue during development (putative) - widely expressed in adult tissue

General

glycoprotein phosphoprotein plexin A

Properties

SIZE: entity length = 1871 aa MW = 208 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-19} Sema {20-488} MOTIF: N-glycosylation site {N59} N-glycosylation site {N548} N-glycosylation site {N637} N-glycosylation site {N738} N-glycosylation site {N746} IPT/TIG 1 {840-933} IPT/TIG 2 {935-1020} MOTIF: N-glycosylation site {N1009} IPT/TIG 3 {1023-1122} MOTIF: N-glycosylation site {N1036} N-glycosylation site {N1073} N-glycosylation site {N1115} IPT/TIG 4 {1125-1211} MOTIF: N-glycosylation site {N1162} transmembrane domain {1221-1241} Ser phosphorylation site {S1607} Ser phosphorylation site {S1610}

Database Correlations

OMIM 300022 UniProt P51805 PFAM correlations Entrez Gene 5363 Kegg hsa:5555

References

UniProt :accession P51805