pleckstrin homology domain-containing family G member 2 (PLEKHG2)

Function: - may be a transforming proto-oncogene protein with exchange activity for CDC42 Structure: - contains 1 DH (DBL-homology) domain - contains 1 PH domain Alternative splicing: named isoforms=3

General

phosphoprotein pleckstrin homology domain containing family

Properties

SIZE: entity length = 1386 aa MW = 148 kD COMPARTMENT: cytoplasm MOTIF: Dbl homology domain {102-283} PH domain {313-411} glutamate-rich region {593-600} MOTIF: glutamate residue (SEVERAL) Ser phosphorylation site {S610} proline-rich region SITE: 1067-1184 MOTIF: proline residue (SEVERAL) proline-rich region SITE: 1319-1328 MOTIF: proline residue (SEVERAL) glycine-rich region {1344-1347}

Database Correlations

UniProt Q9H7P9 PFAM correlations

References

UniProt :accession Q9H7P9