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plasminogen-related protein B (PLGLB1, PLGL, PRGB, PLGLB2, PLGP1)
Function:
- may bind noncovalently to lysine binding sites present in the kringle structures of plasminogen
- this may interfere with binding of fibrin or alpha-2-antiplasmin to plasminogen & may result in the localization of activity at sites necessary for extracellular matrix destruction
Structure: contains 1 PAN domain
Compartment: secreted
General
secreted protein
Properties
SIZE: entity length = 96 aa
MW = 11 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-19}
PAN {20-96}
MOTIF: cysteine residue {C49}
MODIFICATION: cysteine residue {C73}
cysteine residue {C53}
MODIFICATION: cysteine residue {C61}
cysteine residue {C61}
MODIFICATION: cysteine residue {C53}
cysteine residue {C73}
MODIFICATION: cysteine residue {C49}
Database Correlations
OMIM 173340
UniProt Q02325
Pfam PF00024
LOCUS-LINK correlations
KEGG correlations
References
UniProt :accession Q02325