placenta-specific protein 1 (PLAC1)

Function: - role in placental development Structure: - belongs to the PLAC1 family Compartment: secreted Expression: - expressed in placenta. - localizes primarily to differentiated syncytiotrophoblast throughout gestation as well as to a small population of villous cytotrophoblasts - also detected in maternal blood & rapidly disappears following delivery, - not detected in other adult or fetal tissues - up-regulated during trophoblast differentiation & by fibroblast growth factor 7 (FGF-7) in trophoblast cells

General

placental protein secreted protein

Properties

SIZE: MW = 24 kD entity length = 212 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-22}

Database Correlations

OMIM 300296 UniProt Q9HBJ0

References

UniProt :accession Q9HBJ0