nuclear transport factor 2; NTF-2; placental protein 15; PP15 (NUTF2, NTF2)

Function: - facilitates protein transport into the nucleus - interacts with the nucleoporin p62 & with Ran - acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope - could be part of a multicomponent system of cytosolic factors that assemble at the nuclear pore complex during nuclear import Structure: - homodimer - contains 1 NTF2 domain Compartment: cytoplasm

General

placental protein secreted protein

Properties

SIZE: entity length = 127 aa MW = 14 kD COMPARTMENT: cytoplasm MOTIF: NTF2 {10-121}

Database Correlations

OMIM 605813 UniProt P61970 Pfam PF02136 Entrez Gene 10204 Kegg hsa:10204

References

UniProt :accession P61970