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phosphorylated tau217 in dried blood spot
capillary p-tau217 from dried blood spot
Indications:
- screening for Alzheimer's disease
Procedure:
- single finger prick
- single blood drops were applied to a dried plasma spot (DPS) card shipped to a lab (without temperature control or cooling)
- dried plasma spot (DPS) card may be obtained without supervision
- particularly useful in remote & rural settings
Interpretation:
- capillary p-tau217 DPS correlates with plasma ptau-217
- able to discriminate beta-amyloid positive from beta-amyloid negative individuals
- levels provide estimate of cognitive function
Notes:
- additional validation in progress
Related
phosphorylated tau(Thr)217 in serum/plasma (plasma ptau217)
General
microtubule-associated protein tau in body fluid
point of care test
References
- Brooks M
Finger-Prick Test for Alzheimer's Disease?
Medscape. November 01, 2024
https://www.medscape.com/viewarticle/finger-prick-test-alzheimers-disease-2024a1000k1b